Interaction of swine influenza A virus infection with PRRS MLV vaccination in piglets

Patricia Renson (Ifip et Anses) et al., 11th European Symposium of Porcine Management (ESPHM), 22-24 mai 2019, Utrecht, Pays-Bas

Swine influenza A virus (swIAV) is a major respiratory pathogen frequently circulating after weaning, a period commonly used to implement PRRS MLV vaccination in piglets. SwIAV infection was previously shown to induce a strong IFN? response. A recent study also showed that IFN? could abrogate the replication of a PRRSV-2 MLV and the inherent immune response.