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Addition of vitamin E in pigs feed: could prevent cured-meat promotion of colon carcinogenesis in rats

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Aurélie Promeyrat et al., 65th International Congress of Meat Science and Technology (ICOMST), 4-9 août 2019, Potsdam/Berlin, Allemagne, poster

Based on epidemiological studies, excessive consumption of cured meats induces a slight, but significant, increase in the risk of developing colorectal cancer [1]. Among the various hypotheses, recent studies have proposed the central role of heme iron in this positive association. Heme iron catalyzes the formation of genotoxic and cytotoxic nitroso-compound (NOCs) and lipid peroxidation end products (alkenals). Based on the important role of peroxidation and nitrosylation in the effect on cancer risk, our recent studies has made possible to propose a limitation of this effect via the enrichment of cured meat products with vitamin E during their manufacture [2]. In addition, supplementation in pig diet would also appear interesting to protect cured meat from the formation of carcinogenic substances, NOCs and alkenals [3]. In the present study we assess for the first time the effect of adding vitamin E in pig feed on preventing the promotion of colorectal carcinogenesis in rats fed a sausage-based diet from supplemented animals compare to sausage-based diet from control animals .

PDF icon Aurélie Promeyrat et al., 65th ICOMST, 4-9 août 2019, Potsdam/Berlin, Allemagne, poster, PDF icon Aurélie Promeyrat et al., 65th ICOMST, 4-9 août 2019, p. 859-860
2019

Evaluation of Fe, Cu, Mn and Zn in manure of weaned pigs receiving high levels of organic or inorganic supplementation

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A 40 days experiment has been undertaken to evaluate the Fe, Cu, Mn and Zn excretion of piglets given the upper concentrations allowed by European legislation in compound feeds. 40 male and female piglets blocked at an average weight of 8.0 kg (28 days of age) received ad libitum up to 28.6 kg control or experimental diets formulated without phytase. Inorganic (sulfates and oxide) or organic sources were respectively used in control and experimental diets as a supplementation of 110, 150, 50 and 110 mg of Fe, Cu, Mn and Zn elements per kg.

PDF icon Evaluation of Fe, Cu, Mn and Zn in manure of weaned pigs receiving high levels of organic or inorganic supplementation
2009

What mineral and vitamin levels to recommand in swine diets. Que níveis de vitamina e mineral são recomendados em rações de suínos?

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English

Minerals, including trace-elements, and vitamins are currently introduced into the pig diet in order to obtain suitable performances for the modern pig genotype bred in confinement. Most of the mineral and vitamin contents of cereals and usual protein compounds are characterized by their poor and variable availability. Supplemental diets are then usually needed. This paper, based on literature data, reviews the pig requirement for minerals and vitamins in order to ensure economic and profitable performance. Recent research has focused on phosphorus due to environmental considerations. The widespread use of microbial phytase has decreased the need for inorganic phosphates. Cereals are particularly deficient in calcium and sodium, consequently limestone and salt are necessary to meet the pig need for these minerals. Zinc and copper are recognized as growth promoting agents but their use at high levels is detrimental to the environment. The pig diets usually contain supplemental contents of iron, manganese, cobalt, iodine and selenium. The need for these elements in pig diets is described individually. Vitamin E and choline represent the most expensive vitamins added. Choline is then usually not incorporated into the pig fattening diet taking into account the choline contents of the raw materials, while vitamin E is included at a lower level than those which improve the meat quality. Our recent research has dealt with increased levels of vitamins added in combination, calculating higher requirement of the modern pig genotype. Fewer improvements have been obtained in this way, suggesting that recommendations proposed by INRA in 1984 are mainly justified.

Brasileira

Minerais, inclusive elementos traços, e vitaminas são atualmente adicionados nas rações de suínos objetivando obter performance adequada para genótipos modernos criados em confinamento. A maioria do conteúdo de mineral e vitamina dos cereais e compostos protéicos é caracterizada por sua baixa e variável disponibilidade. Dietas suplementares são então geralmente necessárias. Este artigo, baseado em dados de literatura, revê a exigência do suíno para minerais e vitaminas objetivando assegurar desempenho econômico e rentável. Recente pesquisa tem focado no fósforo devido às considerações ambientais. A propagação do uso de fitase microbial reduziu a necessidade de fosfato inorgânico. Cereais são particularmente deficientes em cálcio e sódio, consequentemente calcário e sal são necessários para atender a necessidade do suíno para estes minerais. Zinco e cobre são reconhecidos como agentes promotores de crescimento, mas sua utilização em elevados níveis são prejudiciais ao meio-ambiente. As rações de suínos geralmente contêm quantidades suplementares de ferro, manganês, cobalto, iodo e selênio. A necessidade para estes elementos nas rações de suínos é descrita individualmente. A vitamina E e a colina são as vitaminas mais caras a serem adicionadas. Consequentemente, a Colina não é incorporada na ração de suínos em terminação, levando-se em conta o conteúdo das matérias-primas, enquanto que a vitamina E é incluída em nível mais baixo do que aqueles que melhoram a qualidade da carne. Nossa pesquisa recente lidou com níveis elevados de vitaminas adicionadas em misturas, calculando exigências mais elevadas dos genótipos suínos modernos. Poucos avanços foram obtidos dessa maneira, sugerindo que as recomendações proposta pelo INRA em 1984 são até hoje justificadas.

2009

Analyse de la composition minérale de deux co-produits issus de l'industrie céréalière

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Deux essais de mesures des éléments minéraux sur des co-produits issus de l'amidonnerie de blé ont été menés au cours des années 1999 et 2001. Les résultats obtenus ont permis d'établir une première banque de données sur les éléments minéraux : le calcium, magnésium, sodium, potassium, chlorures et phosphore pour les macro éléments ; le fer, cuivre, zinc et manganèse

pour les oligo-éléments. Toutes ces valeurs permettent de faire une comparaison sur deux

PDF icon Analyse de la composition minérale de deux co-produits issus de l'industrie céréalière
2003

Teneurs en éléments-trace métalliques des aliments et des lisiers de porcs à l'engrais, de truies et de porcelets

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L’objectif de cette étude est de caractériser la composition des aliments et des lisiers de porc par stade physiologique pour 15 éléments-trace. Des bacs en inox disposés sous caillebotis nous permettent de collecter intégralement les lisiers pour leur caractérisation.
PDF icon Teneurs en éléments-trace métalliques des aliments et des lisiers de porcs à l'engrais, de truies et de porcelets
2001

Valeur nutritionnelle

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Composition globable et valeur énergétique

Consommation des charcuteries et équilibre alimentaire

Protéines

Lipides

Glucides

Sel

Fer

Vitamines

Minéraux et oligoéléments

Cholestérol
1999